San Francisco Giants vs St. Louis Cardinals Prediction MLB Picks 6/22/24 (2024)

• Recent betting trends and streaks involving the San Francisco Giants

• Recent betting trends and streaks involving the St. Louis Cardinals

• Recent betting trends in games played between the Giants and Cardinals

• A summary that ties it all together and produces a favorable betting outcome for the Giants vs Cardinals game

San Francisco Giants Betting Preview

In their early-week series, the Giants took on the Chicago Cubs. San Francisco won the Monday game 7-6 but lost the other pair 5-2 and 6-5. In the Thursday series opener versus the Cardinals at Rickwood Field, the Giants took a tough 6-5 loss. Starter Keaton Winn gave up five earned in 2.2 innings on five hits and a walk.

For the starter role in the Saturday matchup, the Giants will send out Jordan Hicks. This year Hicks is 4-3 with a 2.82 ERA and 68 strikeouts.

St. Louis Cardinals Betting Preview

Over on the Cardinals’ side, they played the Miami Marlins in their last series. St. Louis similarly won their opener 7-6 but then lost the next two outings 9-8 and 4-3. The Cardinals got off to a quick start at the plate in Thursday’s game, but Andre Pallante struggled with 5.1 innings and five earned as starter.

Miles Mikolas will take the mound for the Cards on Saturday. This year Mikolas is 5-6 with a 4.59 ERA and 64 strikeouts. Mikolas is 59-59 with a 3.99 career ERA in 193 games (165 starts).

Giants vs Cardinals Pick Injury Notes

Cardinals catcher Ivan Herrera (back) was unavailable to play in Thursday’s game. 3B Nolan Arenado (elbow) was out as well. SP Kyle Gibson (back) is likely to make his next scheduled start Tuesday.

Total Runs Facts

• Ten of the Cardinals' last 11 day games against National League opponents have gone UNDER the total runs line.
• Five of the Giants' last six games against National League opponents have gone OVER the total runs line.
• The 'Inning 1 OVER 0.5 runs' market has hit in each of the Cardinals' last three games.

St. Louis Cardinals Player Prop Facts

• Miles Mikolas has recorded a win in three of his last four appearances against the Giants.
• Matt Carpenter has hit a home run in two of his last three appearances in day games against NL teams that held a losing record.
• Paul Goldschmidt has recorded at least one total base in each of the Cardinals' last 11 games against the Giants at Busch Stadium.
• Miles Mikolas has recorded five or more strikeouts in four of his last five appearances.
• Willson Contreras has scored at least one run in each of his last seven appearances at Busch Stadium.
• Brendan Donovan has recorded at least one RBI in each of the Cardinals' last four games against NL opponents.
• Willson Contreras has recorded a Double in four of his last five appearances in day games against NL teams that held a losing record.
• Paul Goldschmidt has recorded at least one hit in each of the Cardinals' last 11 games against the Giants at Busch Stadium.
• Paul Goldschmidt has recorded at least one Single in each of the Cardinals' last six games against NL West opponents that held a losing record.

San Francisco Giants Player Prop Facts

• Austin Slater has recorded at least one Single in each of his last five appearances against the Cardinals.
• Nick Ahmed has recorded at least one RBI in each of his last three appearances against the Cardinals at Busch Stadium.
• Wilmer Flores has recorded a Double in three of the Giants' last four games against the Cardinals at Busch Stadium.
• Jorge Soler has recorded at least one hit in each of his last nine appearances against the Cardinals.
• Mike Yastrzemski has hit a home run in each of the Giants' last two games at Busch Stadium.
• Jorge Soler has recorded at least one total base in each of his last nine appearances against the Cardinals.
• Michael Conforto has scored a run in each of his last six appearances against the Cardinals after not playing the previous day.

San Francisco Giants vs St. Louis Cardinals Prediction

I’ll just stay with the Cardinals here. Mikolas should do a pretty good job while he’s out there. In his last three starts combined Mikolas is 2-0 with three earned runs in 19.1 innings on 10 hits and one walk. As for Hicks, he struggled a bit early this month but is coming off a nice outing versus the Cubs (5.0 clean frames).

St. Louis had a great first few innings offensively in the Thursday opener but ultimately cooled off and got out-hit 11-7. Only a few players came away with nice stats at the plate. The bats need to get going more consistently Saturday, but Mikolas should be able to set the table well.